{"ATC Code":["A - Alimentary tract and metabolism","A01 - Stomatological preparations","A01A - Stomatological preparations","A01AD - Other agents for local oral treatment","A01AD02 - Benzydamine","G - Genito urinary system and sex hormones","G02 - Other gynecologicals","G02C - Other gynecologicals","G02CC - Antiinflammatory products for vaginal administration","G02CC03 - Benzydamine","M - Musculo-skeletal system","M - Musculo-skeletal system","M01 - Antiinflammatory and antirheumatic products","M01A - Antiinflammatory and antirheumatic products, non-steroids","M01AX - Other antiinflammatory and antirheumatic agents, non-steroids","M01AX07 - Benzydamine","M02 - Topical products for joint and muscular pain","M02A - Topical products for joint and muscular pain","M02AA - Antiinflammatory preparations, non-steroids for topical use","M02AA05 - Benzydamine","QA - Alimentary tract and metabolism","QA01 - Stomatological preparations","QA01A - Stomatological preparations","QA01AD - Other agents for local oral treatment","QA01AD02 - Benzydamine","QG - Genito urinary system and sex hormones","QG02 - Other gynecologicals","QG02C - Other gynecologicals","QG02CC - Antiinflammatory products for vaginal administration","QG02CC03 - Benzydamine","QM - Musculo-skeletal system","QM - Musculo-skeletal system","QM01 - Antiinflammatory and antirheumatic products","QM01A - Antiinflammatory and antirheumatic products, non-steroids","QM01AX - Other antiinflammatory and antirheumatic agents, non-steroids","QM01AX07 - Benzydamine","QM02 - Topical products for joint and muscular pain","QM02A - Topical products for joint and muscular pain","QM02AA - Antiinflammatory preparations, non-steroids for topical use","QM02AA05 - Benzydamine","QR - Respiratory system","QR02 - Throat preparations","QR02A - Throat preparations","QR02AX - Other throat preparations","QR02AX03 - Benzydamine","R - Respiratory system","R02 - Throat preparations","R02A - Throat preparations","R02AX - Other throat preparations","R02AX03 - Benzydamine"],"Absorption, Distribution and Excretion":"Oral doses of benzydamine are well absorbed and plasma drug concentrations reach a peak fairly rapidly and then decline with a half-life of approximately 13 hours. When applied topically, although the local drug concentrations are relatively large, the systemic absorption of topically applied benzydamine is relatively low compared to oral doses. This low topical absorption contributes to a decreased potential for any systemic drug side-effects when benzydamine is administered in this way.","Aliases":["Benzidamine","Benzindamine","Bencidamina","Benzydaminum","Benzidamina","Apo-Benzydamine","1-Benzyl-3-(3-(dimethylamino)propoxy)-1H-indazole","1-Benzyl-3-[3-(dimethylamino)propoxy]-1H-indazole","{3-[(1-benzyl-1H-indazol-3-yl)oxy]propyl}dimethylamine","1-Propanamine, N,N-dimethyl-3-((1-(phenylmethyl)-1H-indazol-3-yl)oxy)-","Chebi:94563","1-Propanamine, N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-","(3-((1-benzyl-1H-indazol-3-yl)oxy)propyl)dimethylamine","Novo Benzydamine","PMS Benzydamine","ratio Benzydamine","Sun Benz","Dtxcid7027835","G02CC03","M02AA05","R02AX03","211-388-8","1H-Indazole, 1-benzyl-3-(3-(dimethylamino)propoxy)-","3-((1-benzyl-1H-indazol-3-yl)oxy)-N,N-dimethylpropan-1-amine","3-[(1-benzyl-1H-indazol-3-yl)oxy]-N,N-dimethylpropan-1-amine","benzydamide","Ncgc00016397-01","Cas-132-69-4","Einecs 211-388-8","C 1523","Brn 0896536","Sr-01000799149","Prestwick0_000297","Prestwick1_000297","Prestwick2_000297","Prestwick3_000297","Schembl26172","BSPBio_000234","5-23-11-00248","Chembl12610","SPBio_002453","BPBio1_000258","orb1219244","orb1298618","Schembl29376229","3-(1-benzylindazol-3-yl)oxy-N,N-dimethyl-propan-1-amine","HMS2090P22","Albb-027259","BBL009932","Bdbm50103598","EBC-26726","Mfcd00864286","STK711092","Akos005530662","DB09084","SB16913","Ncgc00016397-02","Ncgc00016397-07","Ncgc00016397-11","AC-15604","HY-30235","TS-09888","Sbi-0206866.p001","CS-0000176","NS00009149","ST45026210","T8807","D07516","G78294","1benzyl-3-[3-(dimethylamino)propoxy]-1H-indazole","En300-12576563","F866573","Sr-01000799149-2","Brd-k28542495-001-01-4","Brd-k28542495-003-03-6","Brd-k28542495-003-07-7","Brd-k28542495-003-12-7","Brd-k28542495-003-13-5","dimethyl{3-[1-benzyl(1H-indazol-3-yloxy)]propyl}amine","1-Benzyl-1h-indazol-3-yl 3-(dimethylamino)propyl ether","3-[(1-benzyl-1H-indazol-3-yl)oxy]-N,N-dimethylpropan-1-aminie","N,N-dimethyl-3-[[1-(phenylmethyl)-3-indazolyl]oxy]-1-propanamine","N-(3-[(1-Benzyl-1H-indazol-3-yl)oxy]propyl)-N,N-dimethylamine #"],"Biological Half-Life":"Approximately 13 h after oral administration, with a terminal half life of about 7.7 h.","CAS":"642-72-8","ChemicalClasses":["benzylamine"],"Chirality":"achiral","DTXSID":"7047859","Drug Indication":"Available predominantly as a liquid mouthwash, oromucosal spray, or topical cream, benzydamine is most frequently employed as a locally acting analgesic and anti-inflammatory treatment for the relief of painful inflammatory conditions.   When formulated as a mouthwash or spray, benzydamine may be used to treat traumatic conditions like pharyngitis following tonsillectomy or the use of a naso-gastric tube, inflammatory conditions like pharyngitis, aphthous ulcers and oral ulceration due to radiation therapy, dentistry operations and procedures, or more general conditions like sore throat, sore tongue, sore gums, mouth ulcers, or discomfort caused by dentures.   When used as a topical cream, benzydamine may be employed to relieve symptoms associated with painful inflammatory conditions of the muscolo-skeletal system including acute inflammatory disorders such as myalgia and bursitis or traumatic conditions like sprains, strains, bruises, sore muscles, stiff joints, or even the after-effects of fractures.","EliminationHalfLife":"13 hours","Erowid Experience Reports":[],"Esters":[],"European Community (EC) Number":"211-388-8","Formating":[],"HMDB ID":"HMDB0249061","HeavyAtomCount":23,"Human Drugs":"Pharmaceuticals","IUPACName":"3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine","InChI":"InChI=1S/C19H23N3O/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16/h3-7,9-12H,8,13-15H2,1-2H3","InChIKey":"CNBGNNVCVSKAQZ-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M0002384","Link":"https://id.nlm.nih.gov/mesh/M0002384.html","Name":"Benzydamine","Ref":57},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":59},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":80},{"Id":"M0001333","Link":"https://id.nlm.nih.gov/mesh/M0001333.html","Name":"Anti-Inflammatory Agents","Ref":81}],"MeSH Pharmacological Classification":[{"Id":"M0001333","Link":"https://id.nlm.nih.gov/mesh/M0001333.html","Name":"Anti-Inflammatory Agent","Ref":81}],"Mechanism of Action":"Despite being categorized as a non-steroidal anti-inflammatory drug (NSAID), benzydamine demonstrates various mechanisms of action that differ from those of traditional aspirin-like NSAIDs. In particular, benzydamine predominantly acts by inhibiting the synthesis of pro inflammatory cytokines like tumour necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β) without largely affecting other pro inflammatory cytokines (ie. such as IL-6 and IL-8) or anti-inflammatory cytokines (ie. like IL-10 or IL-1 receptor antagonist).  Moreover, benzydamine is largely a weak inhibitor of prostaglandin synthesis as it has been shown to effectively inhibit cyclooxygenase (COX) and lipoxygenase enzyme activity only at concentrations of 1mM or greater. Considering most contemporary usages of benzydamine are topical applications that are generally not well absorbed through the skin and/or non-specialized mucosae, benzydamine does not often achieve the kind of absorption or blood concentrations necessary to cause any extraneous distant systemic effects or COX inhibition, allowing it to localize its action.  Additionally, it is also hypothesized that benzydamine is capable of inhibiting the oxidative burst of neutrophils and membrane stabilization. These actions are exhibited by the substance’s ability to inhibit the release of granules from neutrophils and to stabilize lysosomes.  Furthermore, benzydamine is capable of a local anaesthetic effect that may be related to its capability for inhibiting the release of inflammatory mediators like substance P and calcitonin gene related peptide from sensory nerve endings. Since substance P is capable of causing the release of histamine from mast cells, benzydamine’s prevention of substance P release further contributes to an anti-inflammatory effect.  Benzydamine also demonstrates a non-specific antibacterial activity against various bacterial strains that are resistant to broad-spectrum antibiotics such as ampicillin, chloramphenicol, and tetracycline at concentrations of about 3 mmol/L. Combinatorial use of benzydamine and other antibiotics like tetracycline and chloramphenicol are also synergistic against antibiotic resistant strains of *Staphylococcus aureus* and *Pseudomonas aeruginosa*.","Melting Point":"320°F","Metabolism/Metabolites":"Benzydamine is primarily metabolized by oxidation, dealkylation, and conjugation into hydroxy, dealkylated, and N-oxide metabolites.  In general, however, when used at the recommended doses the levels at which benzydamine is absorbed or exposed into the body are usually not sufficient to produce systemic pharmacological effects [L","MolecularFormula":"C\u003csub\u003e19\u003c/sub\u003eH\u003csub\u003e23\u003c/sub\u003eN\u003csub\u003e3\u003c/sub\u003eO","MolecularWeight":"309.4 g/mol","Pharmacodynamics":"Benzydamine is a non-steroidal anti-inflammatory drug (NSAID) designed to elicit local anesthetic and analgesic effects mainly for the mouth and throat. It specifically acts on the local mechanisms of inflammation such as pain, oedema, or granuloma. Typically applied topically, the drug demonstrates anti-inflammatory activity reducing oedema as well as exudate and granuloma formation. Moreover, benzydamine exhibits analgesic properties and local anaesthetic activity if pain is caused by an inflammatory condition. Benzydamine can be absorbed into the oral mucosa and intact skin. Once absorbed in the local area of pain or inflammation, benzydamine binds selectively to local inflamed tissues, usually allowing it to act with few adverse systemic effects. On average a period of 2 to 4 hours is necessary for the substance to reach peak plasma concentration.   Benzydamine can be synthesized with the reaction of the N-benzyl derivative from methyl anthranilate with nitrous acid to give N-nitoso derivative. This is next reduced by sodium thiosulfate to give transient hydrazine. This hydrazine can then undergo spontaneous internal hydrazide formation. Treating this resultant enolate with 3-chloro-1-dimethylamkino propane ultimately yields benzydamine.","PubChemId":12555,"PubChemTitle":"Benzydamine","Records":{"UNII":{"Impurities":[]}},"Reddit Experience Reports":[{"author":"Imovane666","body":"Note from the start:\nThis trip report is written after sobering up, so it might not contain some of the small details or mini-trips i had during the experience.\n\nHarm reduction:\n\nVERY IMPORTANT INFORMATION:\n\nIf you ever decide to take Tantum Rosa, make sure you filter the salt out, because that will save your kidneys, the start is gonna be way smoother and it might reduce any nausea. Remember that the lethal dosage of salt for humans is calculated as 1 gram of salt per 1 kilogram of body fat. So if you have , for example , 56 kg body weight , you can theoretically ingest a maximum of 56 grams of salt.\n\nOne bag of Tantum Rosa contains 500 mg of benzydamine and ~8.5 g of salt.\n\nIf you dont have a large throat, i do not recomand consuming the powder using the method i did (parachuting), because you might puke, choke, and aside from the taste being unbearable and salty in a horrific way , you could die very easily.\n\nI recommend extracting the benzydamine from the Tantum Rosa bag ( I will put a link for the method of extracting it below) and after you have extracted it succesfully i recommend putting it in/mixing it with orange juice.\nAs i have observed, many other benzydamine users agree on orange juice being the best method to get the most easy to consume (taste-wise) way.\n\n!!!!!!!  HOW TO EXTRACT BENZYDAMINE   !!!!!!!!!!!!\n\nLink 1 (Water extraction):\n(Suitable for table salt)\n\nhttps://www.reddit.com/r/Benzydamine/s/fECYx77dvY\n\nLink 2 (alcohol extraction):\nhttps://www.reddit.com/r/Drugs/s/RiK5aouAA1\n\nEnjoy my horror trip! :D\n\nSetting: My dads house in a small town , i did not go outside at all (thankfully). Most of the trip happened inside the room where i started the trip (around ~9 m² i think by approximating it measured with only my sight and notion of 1 meter, cubic shape , parquet with wooden texture, golden walls with a kind of large paintbrush type of texture in a darker golden , white ceiling with a circle light on it , double glazed door entrance on the right corner of the cube , from entering there is one furniture kit of 2 closets and a table betweem them with a tv sitting on it, and a sofa that turns into a bed on the left side , that bed also being my favourite place to sit from the whole trip and giving me the most enjoyable moments of the whole experience, while being in bed i was snuggled under my dear blanket , being sourrounded by 2 big pillows, 2 small pillows , 1 pink rabbit plushie and 1 cappucino colored teddy bear ) , but some parts also happened in the kitchen, bathroom ,  balcony and hallway.\n\nThe (enclosed) balcony with 3 windows and the medium kitchen (with a big table in the middle and quite a bit of furniture) as well as the narrow but mildly long hallway\nwere the worse places, giving me the most horrifying parts of the trip.\n\nThere where also two more rooms , aside from the bathroom , one at the very beggining of the hallway as you enter the house , and one at the\nvery end.\n\nThe one at the very end was locked, so i did not go there at all, but still hallucinated extra furniture/ sillhouets of people/weird lights or movements through its blurred glass door.\n\nThe room at the beggining wasnt a large part of the trip either , i only remember staying there for 20 minutes just locked in a tilted head , face down position while violently hallucinating, and i remember seeing a lot of spiders and bugs on the bed of that very own room too.\nAlso , weirdly , thats the room where all the shadowy people would hide from me when i tried chasing them.\n\nAlso i mention the house was on the first floor.\n\nTime of day: Night time (trip started around 22:30 , peaked at about 3 to 5 hours from consumption, then the intensity decreased very slowly for the next 24 hours.\n\nI am going to call the main and my favourite room , the cubic shape one , THE SAFE ROOM.\n\nOther rooms will be called by their actual name.\n\n\nT +00:00 :\n(KITCHEN)\n\nJust took (orally) 2 parachutes of benzidamine + salt (2 paper towel baggies containing around 1000 mg of benzidamine and 17 g of salt).\n\nSlight euphoria (might be placebo) after ~2 minutes after i consumed them accompanied by a mild to medium nausea. No puking but i started to salivate excessively.\n\nAte some bread and chocolate after to help me with the taste and prevent me from puking.\n\nT +00:30 :\n(SAFE ROOM)\n\nStill salivating excessively and nauseous, mild tummy ache.\n\nDissapointed for not feeling any strong effects yet.\n\nEuphoria increased but just by a bit, still might be placebo.\n\nT +01:00 :\n(BALCONY)\n\nEuphoria just strong enough to know its not placebo.\n\nAt the 1 hour mark i started to get scared that i wont feel any effects, so i have gone to the balcony to smoke a cigarette , hoping it would help me notice the effects a bit more.\n\nEuphoria certanly increased while/after smoking the cig.\n\nFirst extremely hard to notice visual, very very slight tracers.\n\nT +01:30 :\n\nVisuals starting to kick in.\n\nMild to medium tracers,golden or colorfull outline/aura effect with a weird wavy rainbow texture on it (like the texture when you rub a transparent curtain against itself, wavy colorfull squares increasing and decreasing in size).\n\nEuphoria gets medium to above medium.\n\nNausea gets less noticeable, but still a puking sensation. No puking tho.\n\nOversalivating became mild.\n\nT + 02:00 :        \t=\u003e  The true start\n(SAFE ROOM)         \tof the trip.\n\nOversalivating finally getting more relaxed.\n\nHigh euphoria, very calmed/relaxed mindspace.\nThankfull for finally feeling some noticeable effects.\n\nStrong aura effect (i always notice that this effect in particular is most visible while you are standing in the line where a light and a shadow are meeting each other,light source coming from the left side, touching my pheripheral vision and darkness coming from the right side covering ~ 2/3 of my vision. For me personally, this aura effect  completely dissapears when i go into full light.\n\n\nGot my first really noticeable hallucination by using a method to induce it.\n\nFirst of all, to get hallucinations, you usually need to focus on something. You cant just keep looking around and expect to have mind blowing hallucinations, especially so early into the trip.\nYou gotta concentrate to a specific area.\n\nBasically, the further away the object you are looking at, the higher the chance to get a hallucination.\n\nCovered by my trusty blanket in my warm bed , i looked away at the corner of the hallway and thought to myself that it kinda looked like theres a spider web, but extremely faint and constantly shifting its structure.\n\nThen suddenly: the first hallucination.\n\nA spider with very long legs, and the body of a tarantula.\nIt suddenly appeared from what seemed to be the inside of the wall.\nCrawled a bit with some weird yet extremely realistic movements, and the suddenly jumped right on my face.\n\nThe distance between me and the \"spider\" was a bit far, and the spider just suddenly dissapeared in the air at half the distance.\nStill jumpscared me quite a bit.\n\nI was aware that i was hallucinting and the spider was not actually real.\n\nI managed to recreate the effect a few more times, simply by looking at the same corner again and again and imagining the spider, but each time the hallucination played again, the big spider would be surrounded by more and more small baby spiders (black dots with very small legs).\n\nThis was also the part of the trip when i understood a very important fact:\n\nEspecially in the beggining, (but still applies further in the trip) most hallucinations are induced from your own thoughts. That means that you can pretty much control what you see/manifest any hallucination by just thinking about it (the thing you want to hallucinate).\n\nSo, in fewer words , very cognitive responsive hallucinations.\n\n!!! BE CAREFUL THO as this blessing of being able to manifest any hallucination you want can also be a nightmare in disguise.\nBASICALLY, when you think about something too much, especially later in the trip when your headspace becomes extremely confusing, you cand end up in a thought loop , \"infinitely\" reacreating the same hallucination/hallucinations. If any element of that thought loop/hallucination is also able to scare you or provoke a negative feeling within your self, it is very probable that it will snowball into a bad trip, wich can be extremely unsettleing , absolutely horrendous , VERY ANXIETY INDUCING and potentially traumatizing.\nI have an example of this principle applied further in the trip report.\n\n(COMPLETEAZA CU T+ ACESTUI EXEMPLU)\n\nAlso noticed some more light visual effects, like orbs of faint light orbiting around my pheripherall vision, little noticeable shadow figures in pheripheral vision, seeing bugs but when shifting my sight towards rhem they would dissapear.\n\nMy body felt really warm and very relaxed, my tummy started to burn ( ~2/10 on the pain scale).\n\n\nT +02:30 :\n(SAFE ROOM/KITCHEN)\n\nVery high euphoria accompanied by a feeling of warmth all trough my body (very simmilar to the warmth sensation trihexyphenidil/romparkin or butane huffing/Galaxy Gas/Poppers gives you. Mainly, specific to all inhalants imo.)\n\nAt the 2 hours and a half mark, i started making small trips to the kitchen to drink cold water, as i was starting to get very dihydrated (mainly because of the huge ammount of salt i consumed that was mixed in the composition of tantum rosa).\nThats a very good reason to extract it from the start if you plan on trying the experience, and as a bonus reason,i began feeling a mild pain in my kidneys that is still lasting to the very moment im writing this, more than 24 hours after consumption.\nAlso the aura effect is still kind of visible, slight tracers too.\n\n!!! It had happened to me previously to randomly have the aura effect reappear at full intensity even after a few days after last consumption. Might have something to do with alcohol, as i was sipping on a beer while i first noticed this reoccurence.\n\nSo back to the trip, all previous effects got stronger. Quite a few bugs hallucinations.\n\nAs each minute passed, the effects got stronger and stronger.\n\nThat relaxed mindspace would start slowly turning into an innevitable chaos, no spoilers yet.\n\nRinging sound in my years,wich lasted long after the trip started ending. I think i can still hear it slightly.\n\nT +03:00 :\n(SAFE ROOM/KITCHEN/BATHROOM/HALLWAY/R1 a.k.a first room at the beggining of the hallway)\n\nThis was the point when it started to get crazy real fast. I started hallucinating, i do not remember what i was hallucinating tho. I vaguely remember it being a inhomogeneous mix between multiple places, characters , colors shapes and everything. However, i only remember this description being in my deep sea of thoughts, i can not recall even by a bit how all of that actually looked like/how i perceived these hallucinations.\nI have a few flashbacks and i remember feeling my face melting first,then the rest of my body, and soon the hallucinations would begin melting too, until my whole vision was filled with a weird melting viscous liquid, with tones of gray being very accentuated.\n\nI started exploring the house and mindlessly wandering in every corner of this home, seeing very vivid hallucinations all over the place.\n\nMeanwhile, that euphoric mental state turned to an impossible to understand chaos, and after becoming just that, it mutated even further into what was about to become an increasing intensely horrifying experience.\nI started having paranoia, and auditory hallucinations wich are absolutely impossible to distinguish from real sounds. Every sound i would hear,  would start a chain reaction causing an overwhelming ammount of alternate sounds. Normally , that would not be such a big trouble, but combined with the effect of every sound causing you an extreme wave of fear due to paranoia, it becomes not only mentally exhausting, but over the span of a few hours ends up feeling like a legitimate inhumane act of torture.\n\n(In my case, combine that effect with an early form of paranoid psychosis becoming worse with every time i abuse substances to the maximum, and you got the perfect recipe for a terrifingly unpleasurable experience.)  -wich i loved bc im\n                                                  a freak\n\n\n!!! VERY IMPORTANT SIDE NOTE!!!!\nRegarding paranoia, if you plan on ever using benzydamine,beware , as extreme paranoia is a veeeeeery common side effect.\nEverytime i have consumed this substance, it made me extremely paranoid, even more than a meth head. I dont know if this is the case for everyone, but i would certanly take this aspect into consideration before jumping to the decision of actually ingesting this substance.\n\n\nT +03:30 :\n(ALL OVER THE HOUSE)\n\nAt this point, i was absolutely delirious,i could not formulate a single entire sentence. My short term memory was inexistent, i was constantly forgetting who i am, where i am, what i was doing etc. All of this while still hallucinating violently. All sort of things, but i was too brain fried to remember any visual i was seeing. I cant even remember a single thought wich could have helped me paint a mental picture of what i was seeing at that point. \n\nMy initially euphoric mindspace,was now absolutely and entirely psychotic from whatever i can remember. I was hearing multiple voices, male and female, narrating everything i was doing, i was arguing with them, screaming (but only in my mind, i couldnt move my mouth).\nI was barely conscious.\n\nI kept moving chaotically around the house i think...and then bam.\n\nblacked out\n\nT +04:10 :\n(SAFE ROOM/KITCHEN/BALCONY,HALLWAY)\n\nI have absolutely no idea what i did while blackout. I was totally alone and have no cameras around the house either to see what all of this actually looked like irl. \n\nI only remember a faint flashback that i came to the kitchen again to drink water instinctively and after opening the fridge started hallucinating like crazy inside the fridge.\nI then proceeded to stay in front of the fridge, FRIDGE DOOR OPEN ALL THE WAY, frozen in a weird face down pose,while looking in the fridge for what i assume were ~20 minutes.\n\nOther than that, i have absolutely no idea what the fuck have i done in that time period.\n\nHowever,whats going to happen next is the craziest shit ever, so read everything until the end.\n\nAfter blacking out, i woke up a few times standing, and then when i finally regained counciousness, i was awaken by the worst thing that could have ever happened right then.\n\nMy parents came home a day early.\n\nMy mom woke me up, demanding to know something about some information she recieved about me from someone, and the moment she made me stand and get up from the bed , both her and my dad immediately noticed i was absolutely psychotic and delirious.\n\nI remember this quite vividly.\n\nWhen my dad saw me, he got completely overwhelmed by guilt for his incapacity to stop me from taking substances. This being the case, he immediatel refuged in his room, along with a big bottle of vodka, drowning his imagined \"failure as a father\" through his own substance of choice.\n\nI remember every single detail, and in case you think that the way i described his action is weird, i promise you until the end you are going to get it all.\n       \nOk so\n\nAfter my dad went to his room sippin on his vodka, my mother said we should go have a cigarette and talk a bit about the situation.\n\nI was still absolutely tweaking and i kept falling down, i was constantly saying nonsense, i was very afraid of my hallucinations and would cry to my mom that im seeing them and they want to kill me. I remember it so clear, because , even tho my body was acting this way, some small part of my counsciousness was still absolutely lucid.\nIt was a weird feeling, it was like i was just a spectator or a passager and this substance was controlling my body (and doing a horrible job at it) and i cant describe my state at that time other than absolutely psychotic, extremely paranoid, and very unpredictable.\n\nMy mom then said she has looked through my phone while i was blackout (she put my finger on the fingerprint scanner) and afer asking me who was i out today with and me replying with my girlfriends name, she proceeded to show me 3 voice messages on her whatsapp from a number i couldnt see properly.\n\nIm these 3 messages, it was the voice of my girlfriend saying some bad things about my mom. Now the problem was:\n\nNeither me or my girlfriend had sent any of those vocal messages, not to my mom, not to each other or anyone else.\n\nThis was really weird, as it was clearly my girlfriends voice, and it sounded like we where outside.\n\nShe was also talking about taking substances.\n\nI texted her and not only she didnt have any of the vocal messages either, but she also didnt remember ever saying anything like that.\n\nBut since i was still in a delirious state, i quickly forgot about it.\n\nMy mom was extremely angry and showed me even more proof of bad things i did, and she has lost it totally at this point, screaming and telling me she is going to snitch on me at the police.\n\nI was absolutely shocked, as she wasnt the type of person who would ever say something like that.\n\nHer behaviour made my paranoia even worse than it was already.\nI can remember the exact feeling. The pure extreme fear i was feeling. Despair. Terror. Horror. Enough to make you pray to just die instead of having to put up with those crumbling feelings of anxiety.\n\nI also remember looking at her face,and her face would be constantly morphing,like she was turning into a different person.\n\nA blonde female with a mole on her face. But then she would turn into my mom again.\n\nI said a lot of nonsense to her, then came back to the safe room. She went to the bedroom (Not R1, their bedroom) and started talking with dad.\n\nWhile they were talking i was a bit better as i gained more control over my own mind and body and just layed in bed trying to enjoy the rest of my trip.\n\nI closed my eyes and...\n\nT +04:30 - T + ~08:00 \n(SAFE ROOM)\n\nI closed my eyes and at first i was constantly forgetting i am in bed, and instead i was hallucinating my phone in my hands, and somehow i was texting a friend and my girlfriend at the same time.\n\nBut instead of the messages going through by text, i was actually hearing the whole conversation in my head, in all 3 voices: my voice, my girlfriends voice and my friends voice (just so you can get an idea, at that time my girlfriend was sleeping and my friends phone was broken so there was no way for me to be actually texting them).\n\nAnd somehow at that moment it was making perfect sense in my mind to be texting them and instead of seeing the messages, to hear them in the exact voice, tone, accent , way of speech and personality of both my girlfriend and my friend. AND MY VOICE TOO.\n\nThose conversations were lasting i think about 10-20 minutes, and then i would suddenly open my eyes, try to continue texting, but noticing that i was actuallypressong buttons on a phone that was not in my hands. I was typing in air, my phone was actually charging next to my bed.\n\nI would be shocked, try to reach my phone, could not, get lazy, and then everything all over again.\nI kept having these telephatic conversations for at least 2 hours i think, and i was telling them everything i was experiencing and a lot of important things too. \nAnd i was actually thinking that i am talking to the real them, and so i thought until morning when my gf told me i didnt text her anything the entire night and that our friend had broke his phone and there was no way i texted him either.\nAfter that, i was semi-lucid and expectong for the effects to wear down.\n\nOh but no, this evil poison had another plan for me.\n\nI literally closed my eyes again, and i think i fell asleep or was in a trance like state, because until i opened my eyes again  in the morning (around 6  AM i think?) I had lived at least 4 different days.\nAnd im talking about full days, as in taking breakfast, Meeting with my girlfriend and friends,going out with them in a city close-by to where i actually was, doing different things and all of that shit.\n\nAnd every single time,the day ended with cops trapping us in a circle, gun in hand, and telling us we are going to jail.\n\nThat would instantly activate my benzydamine induced extreme paranoia and i would instantly wake up and realise i was actually in bed (or that was a hallucination too,doesnt matter because thats where i actually was, in bed).\n\nBut i would forget immediately and fall back asleep.\n\nAnd this whole thing lasted for 2 to 3 more hours.\n\nAfter that time has passed...\n\nT +08:00 \n\nI woke up.\n\nAt first, i had no recollection of what had happened. I woke up and forgot i ever took benzydamine at all. However, when i tried to stand up and when my aura effect and ghost hand that was following my real hand, i immediately remembered that i took it and realised i was still tweaking.\n\nIt was not as strong, hallucinations seemed to stop almost completely, my whole body was shaking (i had tremors, and they where bad) my tummy was hurting a bit, my kidneys too, but not too much, i couldnt read at close dkstances, i had to put my phone far from my face to be able to use it.\n\nAnd after texting my gf a bit, beggining to tell her everything that happened the nigh before, i couldnt remember when i fell asleep.\n\nI had actually forgotten completely about the whole thing with my parents.\n\nAfter trying to remember when did i fall asleep, i slowly actually remembered the whole thing.\n\nThe problem was, i couldnt remember if it was real or if i hallucinated it or dreamt it.\n\nAfter an hour or two, i remembered enough details to be about 80% sure it had really happened.\n\nThat brought back my paranoia, and anxiety and a lot of negative emotions. I was like, yupp i messed this shit up i should have just stayed sober, now it too late and im fucked. (As in actual fucked, the situation being a bit delicate with this home).\n\nI was not afraid of my parents punishing me or smth, as i am legally an adult in my country.\n\nI was just extremely afraid, i think it was because of the paranoia.\n\nAnd also dissapointing and making my dad wich i loved suffer.\n\nAnd thinking they have seen everything.\nEverything. My phone too. Now i wont go into details, but what was on that phone was literally going to get me homeless and disowned forever))).\n\nAnd like all that panic was not enough.\n\nMy parents started to behave really weird.\n\nT +09:00 \n(SAFE ROOM)\n\nAND THIS, LADIES AND GENTLEMAN, IS THE FINAL PART. \n\nWhat i am about to say now, absolutely fucked my mind, shattered my sense of reality and made me question my whole existence.\n\nMy parents had woken up too.\nBut they acted very strange.\n\nMy father kept coming to my door frame (the door was open the entire time), he would lean against it (he still looked drunk from the night before) hiding himself behind the wall, and every few seconds he would move to the right just enough for his eye to be able to see me.\n\nHe would to this continuously for 5 minutes, then he would go back to his room, and i could hear him starting to cry.\n\nIn the meanwhile, my mom would get out of the room,and do the same thing, but instead of looking directly with her eye, she would put the camera of her phone over the edge of the door frame and kept taking pictures of me and filming me. When i would move myself so the camera could not reach me, she would move further or farther on the hallway. After 5 minutes, she would go away and dad would come back.\n\nThey did this continuously for 2 hours, and they saw i was awake the whole time. I was waiting for them to give me a speech about responsability, to tell me how wrong i was for what i did and tell me what could i do to make it up for them.\n\nWhen i tried to talk to them they wouldnt respond and they just ran immediately to their room, and say nothing.\nThat really freaked me out. After those 2 hours, my dad went to sleep, i could hear him snorring.\n\nBut my mom did not go to sleep.\n\nAnd so for the next 3 hours, she would constantly take photos of me and videos, i would continuously see the top of her phone raising towards the edge of the doorframe to get pictures and videos of me.\n\nThat led me to chase her everytime i saw the top of the phone, but she would immediately go to R1 (the room at the beggining of the hallway) only letting me see her silouette going in the room for half a second, but when i would open the rooms door, i would either see her silouette again, going past me with an insane speed, or she would be behind the door but as soon as i would move the door she would sprint right back on the hallway, and then si would be back in their room, and she would lock the door.\n\nAfter 3 hours of doing this non-stop, i finally gave up.\n\nSo i decided to try something else.\n\nAnd so i messaged one of my sisters, because i wanted to ask her to ask mom why does she keep filming me and taking photos of me.\n\nShe would do it obssesively too.\n\nBut before i could even ask for that, i asked her to come over and eat togheter with me and my parents, since they would not answer me when i knocked on their door and they locked the door too.\n\nHer reply absolutely mortified me.\n\n\"Bro,our parents are not home, they are out of town until tommorow\".\n\nThat reply shocked me so hard and that benzydamine had fried my brain so much the night before, that i tought it was a test from my parents and that my sister was actually with them in the room too, and they all conspired togheter to take revenge on me.\n\n\nAnd then my reality shattered. As i checked every room of the house, and they were all empty.\n\nTheir room was locked but then their alarm clock standing on their nightwatch right next to their bed soon started ringing. And ringing. AND RINGING.\n\nand nobody answered.\n\nBecause i have been alone the entire night, everything that happened with my parents, all the hours of chasing my mom, all the hours ofnwatching her take photos of me and watching my dad lean against the door frame.\n\nMy dads crying, him getting drunk, me smoking the ciggarette with my mom on the balcony, her showing me the vocal messages. Them being very mad at me, absolutelt everything was actually a hallucination.\n\nWhat shocked me the most is that those where the only things i was sure happened for real. I would see every hair of my dads beard. HIS PORES. I would constantly hear them talking to each other. I would hear my dad cry ,loud and clear. And the whole time i was talking to them, what the fuck was i actually doing? Sitting in bed with my eyes closed? Actually being where this things happened but actually talking to the air?\n\nI have searched within myself for an aswer, but that shit completely mindfucked me.\n\nI am pretty sure, when my sister gave me that message, it snapped me out of my actual timeline into a parallel universes timeline where that entire thing did not actually happen and was a hallucination. And the version of me from that timeline had been transported back to my original timeline, and had tu suffer the consequences instead of me.\n\nIs this shit really this strong, or was this entire trip a perfect combination of my mental illness, this demonic substances effects, and the years of drug abuse on my brain that made this made-up sounding ass trip????????\nEverything just felt so real. I guess some questions will always remain unresolved.\n\n\nDamn.\n\n","body_length":27395,"dose_notes":["only count-based doses found (e.g. pills/tabs) — no weight or substance","partial dose: 1.0 g — substance not identified","partial dose: 56.0 g — substance not identified","partial dose: 500.0 mg — substance not identified","partial dose: 8.5 g — substance not identified","partial dose: 1000.0 mg — substance not identified","partial dose: 17.0 g — substance not identified"],"doselog":[{"note":"T +00:00 :","time":"T+0:00"},{"note":"T +00:30 :","time":"T+0:30"},{"note":"T +01:00 :","time":"T+1:00"},{"note":"At the 1 hour mark i started to get scared that i wont feel any effects, so i have gone to the balcony to smoke a cigarette , hoping it would help me notice the effects a bit more.","time":"T+1:00"},{"note":"T +01:30 :","time":"T+1:30"},{"note":"T + 02:00 :        \t=\u003e  The true start","time":"T+2:00"},{"note":"T +02:30 :","time":"T+2:30"},{"note":"At the 2 hours and a half mark, i started making small trips to the kitchen to drink cold water, as i was starting to get very dihydrated (mainly because of the huge ammount of salt i consumed that was mixed in the composition of tantum rosa).","time":"T+2:00"},{"note":"T +03:00 :","time":"T+3:00"},{"note":"T +03:30 :","time":"T+3:30"},{"note":"T +04:10 :","time":"T+4:10"},{"note":"T +04:30 - T + ~08:00","time":"T+4:30"},{"note":"T +08:00","time":"T+8:00"},{"note":"T +09:00","time":"T+9:00"},{"note":"He would to this continuously for 5 minutes, then he would go back to his room, and i could hear him starting to cry.","time":"T+0:05"},{"note":"They did this continuously for 2 hours, and they saw i was awake the whole time. I was waiting for them to give me a speech about responsability, to tell me how wrong i was for what i did and tell me what could i do to make it up for them.","time":"T+2:00"},{"note":"And so for the next 3 hours, she would constantly take photos of me and videos, i would continuously see the top of her phone raising towards the edge of the doorframe to get pictures and videos of me.","time":"T+3:00"},{"note":"After 3 hours of doing this non-stop, i finally gave up.","time":"T+3:00"}],"doses":[{"amount":1,"quality":"partial","unit":"g"},{"amount":56,"quality":"partial","unit":"g"},{"amount":500,"quality":"partial","unit":"mg"},{"amount":8.5,"quality":"partial","unit":"g"},{"amount":1,"quality":"vague","unit":"cap"},{"amount":1000,"quality":"partial","unit":"mg"},{"amount":17,"quality":"partial","unit":"g"}],"flair":"Other","headers":{"set_setting":"My dads house in a small town , i did not go outside at all (thankfully). Most of the trip happened inside the room where i started the trip (around ~9 m² i think by approximating it measured with only my sight and notion of 1 meter, cubic shape , parquet with wooden texture, golden walls with a kind of large paintbrush type of texture in a darker golden , white ceiling with a circle light on it , double glazed door entrance on the right corner of the cube , from entering there is one furniture kit of 2 closets and a table betweem them with a tv sitting on it, and a sofa that turns into a bed on the left side , that bed also being my favourite place to sit from the whole trip and giving me the most enjoyable moments of the whole experience, while being in bed i was snuggled under my dear blanket , being sourrounded by 2 big pillows, 2 small pillows , 1 pink rabbit plushie and 1 cappucino colored teddy bear ) , but some parts also happened in the kitchen, bathroom ,  balcony and hallway."},"id":"1fmko8k","num_comments":19,"prep_flags":null,"pubdate":"2024-09-22","routes":["intramuscular","oral","smoked"],"score":12,"substances":["Alcohol","Amphetamine","Benzydamine","Chocolate","Methamphetamine"],"time_format":"mixed","title":"The biggest MindFuck i ever had (Benzydamine)","upvote_ratio":0.8799999952316284,"url":"https://reddit.com/r/tripreports/comments/1fmko8k/the_biggest_mindfuck_i_ever_had_benzydamine/"}],"RefChem":"118824","RefCount":4,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Benzydamine","Name":"Benzydamine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q793143","Name":"Benzydamine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB09084","Name":"Benzydamine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/12555","Name":"Benzydamine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=642-72-8","Name":"Benzydamine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0249061","Name":"Benzydamine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/D07516","Name":"Benzydamine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/4O21U048EF","Name":"Benzydamine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID7047859","Name":"Benzydamine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 12555, Benzydamine. Accessed August 22, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/12555\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/12555\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Benzydamine. UNII: 4O21U048EF. Global Substance Registration System. Accessed August 22, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/4O21U048EF\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/4O21U048EF\u003c/a\u003e","Therapeutic Goods (Poisons Standard— June 2025) Instrument 2025. May 1, 2025. Accessed August 22, 2026. \u003ca href=https://www.legislation.gov.au/F2025L00599/asmade/2025-05-28/text/original/pdf\u003ehttps://www.legislation.gov.au/F2025L00599/asmade/2025-05-28/text/original/pdf\u003c/a\u003e"],"SMILES":"CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3","SaltData":[{"AcidCount":1,"Amine":"Benzydamine","AmineCount":1,"Formula":"Cl","Name":"hydrochloride","RName":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 169.399 88.011\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".8\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h170v89H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m141.911 1.088-4.411 9.974M138.517 18.818l6.218 8.515M132.263 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