{"ATC Code":["C - Cardiovascular system","C02 - Antihypertensives","C02K - Other antihypertensives","C02KD - Serotonin antagonists","C02KD01 - Ketanserin","QC - Cardiovascular system","QC02 - Antihypertensives","QC02K - Other antihypertensives","QC02KD - Serotonin antagonists","QC02KD01 - Ketanserin","QD - Dermatologicals","QD03 - Preparations for treatment of wounds and ulcers","QD03A - Cicatrizants","QD03AX - Other cicatrizants","QD03AX90 - Ketanserin"],"Abbreviation":["R-41468","R41468","R-41,468","KJK-945","R-49945","R49945"],"Aliases":["Ketanserine","Ketanserina","Ketanserinum","Ketaserin","3-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione","Serefrex","R-41468","R-41,468","R 41468","R 41,468","NSC-758959","3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione","2,4(1H,3H)-Quinazolinedione, 3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-","CHEBI:6123","Dtxcid103188","R41,468","2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-","3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}quinazoline-2,4(1H,3H)-dione","3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,4(1H,3H)-quinazolinedione","ketensin","3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione","3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-1H-quinazoline-2,4-dione","3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1H-quinazoline-2,4-dione","3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-2,4(1H,3H)-quinazolinedione","3-{2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl}-2,4(1H,3H)-quinazolinedione","C02KD01","277-680-2","R41468","C22h22fn3o3","Kentanserin","Mfcd00083392","[3H]-Ketanserin","CHEMBL51","3-(2-(4-(p-Fluorobenzoyl)piperidino)ethyl)-2,4-(1H,3H)-quinazolinedione","3-[2-[4-(4-fluorobenzoyl)-1-piperidyl]ethyl]-1H-quinazoline-2,4-dione","[3H]ketanserin","Ncgc00021146-06","Perketal","Taseron","3-[2-[4-(4-fluorophenyl)carbonylpiperidin-1-yl]ethyl]-1~{H}-quinazoline-2,4-dione","3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione","Cas-74050-98-9","Einecs 277-680-2","Vulketan Gel","R-41-468","3-[2-[4-(p-Fluorobenzoyl)piperidino]ethyl]-2,4-(1H,3H)-quinazolinedione","3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4(1H,3H)-quinazolinedione; Ketanserin; Ketensin; R 41468; Suffrexal; Vulketan Gel","Tocris-0908","Spectrum2_001713","Biomol-NT_000096","GTPL88","3-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)-ethyl)quinazoline-2,4(1H,3H)-dione","Schembl34294","GTPL197","Mls006010073","Spectrum1505346","SPBio_001726","BPBio1_001356","orb1224099","orb1309882","Schembl29361038","BDBM21395","GLXC-06518","HMS1923O11","HMS2090H18","HMS2094I03","HMS3655H14","HMS3887G17","HMS5087J17","Pharmakon1600-01505346","Tox21_110865","CCG-39512","EBC-08725","HY-10562R","NSC758959","Pdsp1_000639","Pdsp2_000634","s2232","Akos015895130","Tox21_110865_1","AC-2024","CS-6055","DB12465","FF24757","GS-3601","Sdccgsbi-0051158.p004","3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4(1H,3H)-quinazolinedione","3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)quinazoline-2,4(1H,3H)-dione","3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione","Ncgc00021146-01","Ncgc00021146-02","Ncgc00021146-03","Ncgc00021146-04","Ncgc00021146-05","Ncgc00021146-07","Ncgc00021146-08","Ncgc00021146-09","Ncgc00021146-12","Ncgc00021146-22","Ncgc00024865-01","Ncgc00024865-02","Ncgc00024865-03","Ncgc00024865-04","Ncgc00024865-05","HY-10562","Smr001550601","SY053064","Sbi-0051158.p003","DB-055834","K0051","K1678","NS00001319","SW196882-3","C07464","D02363","M05722","L000764","R41 468","Brd-k49671696-001-02-1","Brd-k49671696-001-05-4","Brd-k49671696-045-08-5","Brd-k49671696-046-01-8","Brd-k49671696-347-02-8","F2173-1039","Z2216887910","KETANSERIN, Ketanserin tartrate hydrate, KETANSERIN TARTRATE","3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione #","3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]-ethyl]-2,4-[1H, 3H]-quinazolinedione","3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,4-(1H,3H)-quinazolinedione","3-[2-[4-(4-Fluorobenzoyl)-1-piperidyl]ethyl]quinazoline-2,4(1H,3H)-dione","3-{2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-ethyl}-1h-quinazoline-2,4-dione","UYX"],"CAS":"74050-98-9","ChemicalClasses":["benzylamine"],"Chirality":"achiral","DTXSID":"3023188","EliminationHalfLife":"3.5 – 29 hours\u003ca href='#cite_note-3'\u003e\u003csup\u003e[3]\u003c/sup\u003e\u003c/a\u003e\u003ca href='#cite_note-4'\u003e\u003csup\u003e[4]\u003c/sup\u003e\u003c/a\u003e","Esters":[],"European Community (EC) Number":"277-680-2","Formating":[],"HMDB ID":"HMDB0253783","HeavyAtomCount":29,"IUPACName":"3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione","InChI":"InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)","InChIKey":"FPCCSQOGAWCVBH-UHFFFAOYSA-N","MeSH Headers":[{"Id":"M0011983","Link":"https://id.nlm.nih.gov/mesh/M0011983.html","Name":"Ketanserin","Ref":54},{"Id":"M0353421","Link":"https://id.nlm.nih.gov/mesh/M0353421.html","Name":"R-41,468","Ref":56},{"Id":"DescTree","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":"MeSH Tree","Ref":57},{"Id":"PubMed from MeSH","Link":"https://www.nlm.nih.gov/mesh/meshhome.html","Name":null,"Ref":80},{"Id":"M0001456","Link":"https://id.nlm.nih.gov/mesh/M0001456.html","Name":"Antihypertensive Agents","Ref":81},{"Id":"M0017012","Link":"https://id.nlm.nih.gov/mesh/M0017012.html","Name":"Platelet Aggregation Inhibitors","Ref":82},{"Id":"M0019685","Link":"https://id.nlm.nih.gov/mesh/M0019685.html","Name":"Serotonin Antagonists","Ref":83}],"MeSH Pharmacological Classification":[{"Id":"M0001456","Link":"https://id.nlm.nih.gov/mesh/M0001456.html","Name":"Antihypertensive Agent","Ref":81},{"Id":"M0017012","Link":"https://id.nlm.nih.gov/mesh/M0017012.html","Name":"Platelet Aggregation Inhibitor","Ref":82},{"Id":"M0019685","Link":"https://id.nlm.nih.gov/mesh/M0019685.html","Name":"Serotonin Antagonist","Ref":83}],"MolecularFormula":"C\u003csub\u003e22\u003c/sub\u003eH\u003csub\u003e22\u003c/sub\u003eFN\u003csub\u003e3\u003c/sub\u003eO\u003csub\u003e3\u003c/sub\u003e","MolecularWeight":"395.4 g/mol","PubChemId":3822,"PubChemTitle":"Ketanserin","Records":{"UNII":{"Impurities":[]}},"RefChem":"389088","RefCount":5,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Ketanserin","Name":"Ketanserin","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q415997","Name":"Ketanserin","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/DB12465","Name":"Ketanserin","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/3822","Name":"Ketanserin","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=74050-98-9","Name":"Ketanserin","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0253783","Name":"Ketanserin","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C07464","Name":"Ketanserin","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/97F9DE4CT4","Name":"Ketanserin","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID3023188","Name":"Ketanserin","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 3822, Ketanserin. Accessed August 10, 2026. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/3822\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/3822\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Ketanserin. UNII: 97F9DE4CT4. Global Substance Registration System. Accessed August 10, 2026. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/97F9DE4CT4\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/97F9DE4CT4\u003c/a\u003e","Cold GE, Dahl BL. Topics in Neuroanaesthesia and Neurointensive Care: Experimental and Clinical Studies upon Cerebral Circulation, Metabolism and Intracranial Pressure. Springer Science \u0026 Business Media. November 11, 2013. Accessed August 10, 2026. \u003ca href=https://books.google.com/books?id=cYnqCAAAQBAJ\u0026pg=PA193}\u003ehttps://books.google.com/books?id=cYnqCAAAQBAJ\u0026pg=PA193}\u003c/a\u003e","Antihypertensive Drugs Today. VSP. 1992. 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