Enflurane
| Enflurane | |
|---|---|
 | |
| Molecular structure via molpic based on CDK |
| Rotamer [] | |
|---|---|
| Conformer structure via 3Dmol.js |
| Physical properties [] | |
|---|---|
| Molecular mass | 184.49 g/mol [1] |
| Density | 1.52 at 77 °F (NIOSH, 2024) - Denser than water; will sink g/cm3 [1] |
| Appearance | Clear, colorless liquid [1] |
| Odor | Mild, sweet odor [1] |
| Boiling point | 134 ° [1] |
| Decomposition | Hazardous decomposition products formed under fire conditions. - Carbon oxides, hydrogen chloride gas, hydrogen fluoride. [1] |
| Solubility | Low (NIOSH, 2024) [1] |
| Predicted LogP | 2.1 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C3H2ClF5O [1] |
| IUPAC name | 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane [1] |
| SMILES | C(C(OC(F)F)(F)F)(F)Cl [1] |
| InChI | InChI=1S/C3H2ClF5O/c4-1(5)3(8,9)10-2(6)7/h1-2H [1] |
| InChIKey | JPGQOUSTVILISH-UHFFFAOYSA-N [1] |
Enflurane (also known as Methylflurether, 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane, Efrane, Ethrane, 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether, Alyrane, Compound 347, Anesthetic 347, Anesthetic Compound No. 347 or OHIO 347) is a
Chemistry
Stereochemistry []
Enflurane is a racemic mixture of the enantiomers.
| Stereoisomerism |
|---|
| Stereoisomer enumberation with rdkit |
Pharmacology
ATC Classification
In the nervous system (N) enflurane acts as a anesthetic (N01), anesthetics, general (N01A), enflurane (N01AB04) and halogenated hydrocarbon (N01AB).[1]Legal status []
- Brazil: Enflurane is a C1 substance.[3]
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3226, Enflurane. Accessed August 24, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/3226
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Enflurane. UNII: 91I69L5AY5. Global Substance Registration System. Accessed August 24, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/91I69L5AY5
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed August 24, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992