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Sildenafil

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Viagra
Sildenafil
Salts
[]
Sildenafil citrate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Rotamer
[]
Conformer structure via 3Dmol.js
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Physical properties
[]
474.6 g/mol [1]
AppearanceCrystals [1]
Melting point189-190 °C [1]
SolubilityWhite to off-white crystalline powder; solubility in water: 3.5 mg/mL /Sildenafil citrate/ [1]
1.5 [1]
Structural Identifiers
[]
C22H30N6O4S [1]
5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-7-one [1]
CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C [1]
InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29) [1]
InChIKeyBNRNXUUZRGQAQC-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-life3 – 4 hours
Dosing[]
Oral
[]
Light≤ 35 mg(2x - 28.6%)
Common35 - 50 mg(5x - 71.4%)
Strong50 mg
Heavy50 mg
Extreme50 mg +
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Sildenafil (also known as Aphrodil, Vizarsin, Sildenafilo, Patrex, Sildenafil teva, Sildenafil actavis, 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine, HIP0908, HIP-0908 or CHEBI:9139) is a substance of the piperazine class.

Chemistry

Salts []

Sildenafil is typically found in the form of its citrate salt.

 []

Sildenafil is a achiral mixture.

Pharmacology

In the () sildenafil acts

Subjective effects []

alina / Sildenafil []
Routes:
  • Oral (50.0mg)
emily / Sildenafil []
Routes:
  • Oral (63 - 80mg)
Pilz / Sildenafil []
Routes:
  • Oral (22 - 27mg)
Salts:
  • Citrate
Indication:Effects:
  • s are easier to get and more intense

 []

  • Australia: Sildenafil is a S4 substance.
  • Canada: Sildenafil is a prescription only substance.
  • United Kingdom: Sildenafil is a prescription only substance.[3][4]
  • United States: Sildenafil is a prescription only substance.
  • European Union: Sildenafil is a prescription only substance.

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 135398744, Sildenafil. Accessed August 24, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/135398744

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Sildenafil. UNII: 3M7OB98Y7H. Global Substance Registration System. Accessed August 24, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/3M7OB98Y7H

  3. Viagra 25mg film-coated tablets Summary of Product Characteristics (SmPC). September 30, 2024. Accessed August 24, 2026. https://www.medicines.org.uk/emc/product/1072/smpc

  4. Viagra Connect 50 mg film-coated tablets Summary of Product Characteristics (SmPC). May 16, 2024. Accessed August 24, 2026. https://www.medicines.org.uk/emc/product/8725/smpc