Isoflurane
| Isoflurane | |
|---|---|
 | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 184.49 g/mol [1] |
| Density | Specific gravity: 1.45 g/cm3 [1] |
| Appearance | Clear, colorless liquid [1] |
| Odor | Slight odor [1] |
| Melting point | 48-48.5 [1] |
| Boiling point | 48.5 °C [1] |
| Decomposition | When heated to decomposition it emits toxic fumes of /fluorine and chlorine/. [1] |
| Solubility | In water, 4.47X10+3 mg/L at 37 °C [1] |
| Predicted LogP | 2.1 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C3H2ClF5O [1] |
| IUPAC name | 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane [1] |
| SMILES | C(C(F)(F)F)(OC(F)F)Cl [1] |
| InChI | InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H [1] |
| InChIKey | PIWKPBJCKXDKJR-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | ~10 minutes |
Isoflurane (also known as 1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether, Forane, 2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, Forene, Aerrane, Isoflurano, Compound 469, IsoFlo, Isofluranum or Ethane, 2-chloro-2-(difluoromethoxy)-1,1,1-trifluoro-) is a
Chemistry
Stereochemistry []
Isoflurane is a racemic mixture of the enantiomers.
| Stereoisomerism |
|---|
| Stereoisomer enumberation with rdkit |
Pharmacology
ATC Classification
In the nervous system (N) isoflurane acts as a anesthetic (N01), anesthetics, general (N01A), halogenated hydrocarbon (N01AB) and isoflurane (N01AB06).[1]Legal status []
- Brazil: Isoflurane is a C1 substance.[3]
- United Kingdom: Isoflurane is a prescription only substance.
- United States: Isoflurane is a prescription only substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3763, Isoflurane. Accessed August 24, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/3763
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Isoflurane. UNII: CYS9AKD70P. Global Substance Registration System. Accessed August 24, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/CYS9AKD70P
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed August 24, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992