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Desflurane

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Desflurane
Desflurane
Molecular structure via molpic based on CDK
Rotamer
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Conformer structure via 3Dmol.js
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Physical properties
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168.04 g/mol [1]
Density1.44 g/cm3 [1]
AppearanceLiquid [1]
OdorSlight non-pungent odor [1]
Boiling point23.5 °C [1]
SolubilityNegligible [1]
2.6 [1]
Structural Identifiers
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C3H2F6O [1]
2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane [1]
C(C(F)(F)F)(OC(F)F)F [1]
InChI=1S/C3H2F6O/c4-1(3(7,8)9)10-2(5)6/h1-2H [1]
InChIKeyDPYMFVXJLLWWEU-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-lifeElimination dependent on minute ventilation

Desflurane (also known as Suprane, Desflurano, difluoromethyl 1,2,2,2-tetrafluoroethyl ether, Desfluranum, I-653, I 653, 2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether, 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane, Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro- or CHEBI:4445) is a substance of the ether class.

Chemistry

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Desflurane is a racemic mixture of the .

(R)-DesfluraneGenerated by the Chemistry Development Kit (http://github.com/cdk)
(S)-DesfluraneGenerated by the Chemistry Development Kit (http://github.com/cdk)
Stereoisomer enumberation with rdkit

Pharmacology

In the () desflurane acts as a anesthetic (), anesthetics, general (), desflurane () and halogenated hydrocarbon ().[1]

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  • Australia: Desflurane is a S4 substance.
  • Brazil: Desflurane is a C1 substance.[3]
  • United States: Desflurane is a prescription only substance.

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 42113, Desflurane. Accessed August 24, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/42113

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Desflurane. UNII: CRS35BZ94Q. Global Substance Registration System. Accessed August 24, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/CRS35BZ94Q

  3. Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed August 24, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992